【MMP-3】Matrix Metalloproteinase-3 (Latex Immunoturbidimetric Method)

Background of Clinical Indications

Rheumatoid arthritis (RA) is a common autoimmune disease characterized by chronic inflammation of the joint synovium. Its main pathological feature is continuous joint synovial inflammation and cell infiltration, eventually involving cartilage and bone, leading to joint structural damage, deformity and dysfunction, causing different degrees of disability. MMP-3 is considered as the most critical protease for the degradation of articular cartilage. It is expressed at a high level in the peripheral blood of patients with RA. It is related to RA disease activity, closely related to RA joint damage, and can be used as an indicator to predict joint damage.