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Background of Clinical Indications
Streptococcal hemolysin "O" is one of the metabolites of group A hemolytic streptococci. It is a protein with hemolytic activity and antigenicity. The anti-streptolysin "O" (ASO) in normal humans has a certain basic value. After hemolytic streptococcus infection, ASO increases, so ASO has become an important indicator for judging streptococcal infection. Increased streptococcal hemolysin "O" is common in patients with diseases such as rheumatic fever, hemolytic streptococcal infection, and acute glomerulonephritis. In addition, Coxsackie B virus, hypercholesterolemia, hemolysis, hepatitis, nephrotic syndrome and other diseases can show non-specific anti-"O" increase.