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Background of Clinical Indications
It is used for the auxiliary diagnosis of rickets, osteomalacia and other bone diseases, as well as obstructive jaundice and other diseases. Increased: seen in patients with obstructive jaundice, hepatic cirrhosis, hepatic necrosis (increase is not obvious in hepatocellular jaundice); primary and secondary hepatic disorders. It can also be seen in patients with osteitis deformans, osteoblast disease, rickets, osteomalacia, hyperthyroidism, hyperparathyroidism and renal tubular acidosis. Decreased: common in patients with severe chronic nephritis, celiac disease, anemia, cachexia, thyroid insufficiency or hypothyroidism in children, malnutrition, and cretinism.