Let us create a wonderful future together!
Background of Clinical Indications
Increased level of low-density lipoprotein cholesterol (LDL-C) is an independent risk factor for atherosclerosis, while sdLDL-C has a lower affinity for LDL-C receptors, a longer plasma half-life, and slow clearance; sdLDL-C is small in size, and thus has stronger penetrating power to the arterial intima; sdLDL-C is easier to be oxidized and taken up by macrophages to form foam cells, which are deposited on the inner wall of blood vessels, causing sdLDL-C to be more likely to cause atherosclerosis. sdLDL-C is an important marker of cardiovascular disease and a risk factor for coronary heart disease.