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Background of Clinical Indications
It is used for the auxiliary diagnosis of anemia and renal disorder. Increased: common in patients with decreased synthesis of transferrin, non-iron deficiency anemia, various types of iron deficiency anemia, hemolytic anemia, aplastic anemia, and macrocytic anemia. Decreased: common in patients with hepatic cirrhosis and nephrotic syndrome. The maximum amount of iron bound by transferrin in serum is called total iron binding capacity, which is equivalent to the sum of serum iron and unsaturated iron.